Follicular mucinosis is a term that encompasses three related entities. Alopecia mucinosa, Urticaria-like follicular mucinosis, and cutaneous lymphoma related. On hair-bearing skin (e.g. scalp), overlying alopecia is notable, hence the term “ alopecia mucinosa” (see Figure 5). Plaques are often composed of densely. Alopecia mucinosa is a skin disorder that generally presents, but not exclusively, as erythematous plaques or flat patches without hair primarily on the scalp.

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An electron microscopic study. While response to dapsone in the first six cases and minocycline in the last case is possible, the most consistent common factor in all cases seems to be antileprosy treatment.

With the results of the biopsy, however, these cases would be diagnosed as Alopecia mucinosa! Alopecia mucinosa most commonly affects face, neck and scalp, but any part of the body may be affected. Given the association with CTCL, as well as much rarer associations with other hematologic malignancies e.

This condition of the skin appendages article is a stub.

Caution if used in patients with gastritis, peptic ulcer disease, or renal insufficiency. Open in a separate window. Cell mediated immune mechanisms play a role in the pathogenesis of follicular mucinosis and T lymphocytes that infiltrate follicular epithelium may lead to destructive changes in the follicular keratinocytes to produce mucin. FM may affect children it is very rare in infants and toddlersbut is most common in the 4th to 6th decades.

Introduction What was known? Ingrown nail Anonychia ungrouped: Hirsutism Acquired localised generalised patterned Congenital generalised localised X-linked Prepubertal.

Follow up in September 09, 3.

Alopecia mucinosa

When incidentally encountered microscopically, mycinosa may be simply viewed as a histologic reaction pattern. No sponsor or advertiser has participated in, approved or paid for the content provided by Decision Support in Medicine LLC. Accessed December 31st, By registering you consent to the collection and use of your information to provide the products and services you have requested from us and as described in our privacy policy and terms and conditions.


We report three cases to apopecia to four similar cases reported earlier by one of the authors. It may persist for months or years and no specific therapy has been found to be effective for patients with idiopathic alopecia mucinosa.

Case Reports Case 1 A year-old boy presented in Septemberwith a hypopigmented and hypoaesthetic shiny patch on the left cheek of few months duration. Home About Us Advertise Amazon.

Pathology Outlines – Alopecia mucinosa

Two children, a boy aged 14 years and a girl aged 12 years presented themselves, each, with a single hypopigmented, hypoesthetic patch on the face. Body odor Chromhidrosis Fox—Fordyce disease. Based on histological findings these cannot be diagnosed as leprosy and will be considered as Alopecia mucinosa. A year-old girl presented in Marchwith hair loss over left eyebrow and dry hypopigmented skin of adjacent forehead.

Case 2 A year-old girl presented in Marchwith hair loss over left eyebrow and dry hypopigmented skin of adjacent forehead. Minocycline has been used in treatment of Alopecia Mucinosa, and minocycline in ROM may be the responsible for healing in case 3: Clinical, histological and immunological remission with minocycline.

National Center for Biotechnology InformationU. Abstract Three cases with single lesion of Alopecia mucinosa follicular mucinosis were treated with antileprosy treatment and showed rapid and complete resolution of the lesions with no recurrence on extended follow-up.

Follicular mucinosis presenting as acute dermatitis with response to dapsone. A reaction pattern in follicular epithelium. In this article we describe three cases, two children with a single facial lesion clinically suspected to be leprosy in whom biopsy showed follicular mucinosis without granulomas.

New author database being installed, click here for details. The third case, male, aged 22 years presented with a single erythematous, hypoesthetic plaque on mucinosz forehead.

Mucins look like stringy clear or whitish goo mainly composed of hyaluronic acid, a normal component of the ground substance surrounding collagen in the dermis. Superficial and deep, perivascular and perifollicular, infiltrate of lymphocytes and numerous eosinophils.


Usually, primary and acute alopecia mucinosa occurring in children resolves spontaneously.

Follicular Mucinosis (Alopecia Mucinosa)

Journal List Indian J Dermatol v. The biopsy showed a moderately akopecia superficial and mid perivascular infiltrate of lymphocytes with occasional eosinophils without any granulomas in the sections.

Paronychia Acute Chronic Chevron nail Congenital onychodysplasia of the index fingers Green nails Half and half nails Hangnail Hapalonychia Hook nail Ingrown nail Lichen planus of the nails Longitudinal erythronychia Malalignment of the nail plate Median nail dystrophy Mees’ lines Melanonychia Muehrcke’s lines Nail—patella syndrome Onychoatrophy Onycholysis Onychomadesis Onychomatricoma Onychomycosis Onychophosis Onychoptosis defluvium Onychorrhexis Onychoschizia Platonychia Pincer nails Plummer’s nail Psoriatic nails Pterygium inversum unguis Pterygium unguis Purpura of the nail bed Racquet nail Red lunulae Shell nail syndrome Splinter hemorrhage Spotted lunulae Staining of the nail plate Stippled nails Subungual hematoma Terry’s nails Twenty-nail dystrophy.

Clinically leprosy was suspected, however, skin biopsy from both patients revealed follicular mucinosis as the only pathological finding, without any granulomas. Retrieved from ” https: Hair nails and sweat disorders. Several lymphocytes were seen infiltrating the affected follicular infundibula. The number of lesions ranges from one or two to several dozen; they are typically distributed on the alipecia, scalp, or neck; the trunk and extremities are less often affected. Characteristic findings on physical examination Lesions are often asymptomatic but may itch or burn; they develop over weeks or months not days.

Alopeciq Controversy exists as to whether the disease is a nucinosa process or a reactive process. Are You Confident of the Diagnosis? Follicular mucinosis as the alopexia pathology may be seen in facial alopeca of clinically suspected leprosy in children and young adults. Vanessa Ngan, Staff Writer, Mycosis fungoides associated follicular mucinosis on posterior scalp.